Journal of Prosthetic Dentistry
Volume 90, Issue 5 , Pages 452-458 , November 2003

In vitro cytotoxicity of traditional versus contemporary dental ceramics

  • Regina L.W Messer, PhD

      Affiliations

    • Assistant Professor of Dentistry, Dept. of Oral Biology, Augusta, Ga., USA
    • ,
  • Petra E Lockwood

      Affiliations

    • Research Assistant, Dept. of Oral Rehabilitation, Augusta, Ga., USA
    • ,
  • John C Wataha, DMD, PhD

      Affiliations

    • Professor of Dentistry, Dept. of Oral Rehabilitation, Augusta, Ga., USA
    • Corresponding Author InformationReprint requests to: Dr John C. Wataha, AD-3271, Medical College of Georgia School of Dentistry, Augusta, GA 30912-1260, USA, FAX: (706) 721-8349
    • ,
  • Jill B Lewis, PhD

      Affiliations

    • Associate Professor of Dentistry, Dept. of Oral Biology, Geneva, Switzerland
    • ,
  • Samuel Norris, DMD

      Affiliations

    • Graduate Dental Student in Periodontics, Geneva, Switzerland
    • ,
  • Serge Bouillaguet, DMD, PD

      Affiliations

    • Associate Professor of Dentistry, Department of Cariology and Endodontics, University of Geneva, Geneva, Switzerland

References 

  1. Giordano RA. Dental ceramic restorative systems. Compend Contin Educ Dent. 1996;17:779–794
  2. Deany IL. Recent advances in ceramics for dentistry. Crit Rev Oral Biol Med. 1996;7:134–143
  3. Anusavice KJ. Recent developments in restorative dental ceramics. J Am Dent Assoc. 1993;124:72–84
  4. Drummond JL, King TJ, Bapna MS, Koperski RD. Mechanical property evaluation of pressable restorative ceramics. Dent Mater. 2000;16:226–233
  5. Wataha JC. Principles of biocompatibility for dental practitioners. J Prosthet Dent. 2001;86:203–209
  6. Cobb CM, White CL, Gillahan DR, Tira DE. In vitro compatibility of air-fired opaque porcelain with human gingival fibroblasts. J Prosthet Dent. 1988;59:187–194
  7. Li J, Liu Y, Hermansson L, Soremark R. Evaluation of biocompatibility of various ceramic powders with human fibroblasts in vitro. Clin Mater. 1993;12:197–201
  8. Wataha JC. Alloys for prosthodontic restorations. J Prosthet Dent. 2002;87:351–363
  9. Wataha JC. Biocompatibility of dental casting alloys (a review). J Prosthet Dent. 2000;83:223–234
  10. Schmalz G, Garhammer P. Biological interaction of dental cast alloys with oral tissues. Dent Mater. 2002;18:396–406
  11. Wataha JC, Nakajima H, Hanks CT, Okabe T. Correlation of cytotoxicity with elemental release from mercury- and gallium-based dental alloys in vitro. Dent Mater. 1994;10:298–303
  12. Wataha JC, Rueggeberg FA, Lapp CA, Lewis JB, Lockwood PE, Ergle JW, et al.  In vitro cytotoxicity of resin-containing restorative materials after aging in artificial saliva. Clin Oral Investig. 1999;3:144–149
  13. Nelson SK, Wataha JC, Neme A-ML, Cibirka RM, Lockwood PE. Cytotoxicity of dental casting alloys pretreated with biologic solutions. J Prosthet Dent. 1999;81:591–596
  14. Nelson SK, Wataha JC, Lockwood PE. Accelerated toxicity testing of casting alloys and reduction of intraoral release of elements. J Prosthet Dent. 1999;81:715–720
  15. Geis-Gerstorfer J, Sauer KH, Pässler K. Ion release from Ni-Cr-Mo and Co-Cr-Mo casting alloys. Int J Prosthodont. 1991;4:152–158
  16. Kokoti M, Sivropoulou A, Koidis P, Garefis P. Comparison of cell proliferation on modified dental ceramics. J Oral Rehabil. 2001;28:880–887
  17. Milleding P, Haraldsson C, Karlsson S. Ion leaching from dental ceramics during static in vitro corrosion testing. J Biomed Mater Res. 2002;61:541–550
  18. Anusavice KJ. Degradability of dental ceramics. Adv Dent Res. 1992;6:82–89
  19. Wataha JC, Lockwood PE. Release of elements from dental casting alloys into cell-culture medium over 10 months. Dent Mater. 1998;14:158–163
  20. International Standards Organization. Biological evaluation of medical devices: Part 5: Tests for Cytotoxicity: In vitro methods 1992; ISO 10993-5:1992(E), Geneva Switzerland
  21. Wataha JC, Craig RG, Hanks CT. Precision of and new methods for testing in vitro alloy cytotoxicity. Dent Mater. 1992;8:65–70
  22. Hanks CT, Wataha JC, Sun Z. In vitro models of biocompatibility (a review). Dent Mater. 1996;12:186–193

☆ Funding provided by Metalor Technologies SA, Neuchatel, Switzerland.

PII: S0022-3913(03)00533-X

doi: 10.1016/S0022-3913(03)00533-X

Journal of Prosthetic Dentistry
Volume 90, Issue 5 , Pages 452-458 , November 2003

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