Abstract
Statement of problem
Whether oral rehabilitation with dental implants in patients with Down syndrome leads
to an increased complication rate is unclear.
Purpose
The purpose of this systematic review was to determine the effectiveness of dental
implants placed in patients with Down syndrome and whether the condition is a risk
factor or contraindication for dental implant placement.
Material and methods
Searches were conducted in 6 databases, including the non–peer-reviewed literature,
up to February 2021 by 2 independent reviewers according to established inclusion
and exclusion criteria to answer this question: Is Down syndrome a risk factor or
contraindication for oral rehabilitation with dental implants?
Results
A total of 655 studies were initially found in the databases. Five were included in
this systematic review, all of which were observational studies. A total of 50 patients
with 186 implants were evaluated, with a reported effectiveness of 79.1%. The risk
of bias assessment determined that 3 of the 5 studies had a high risk of bias.
Conclusions
Treatment with dental implants in patients with Down syndrome is a suitable option,
but more complications are to be expected than with patients without this condition.
Controlled studies with better methodological design and less risk of bias should
be developed to improve the scientific evidence for the treatment of these patients.
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Article info
Publication history
Published online: July 28, 2021
Publication stage
In Press Corrected ProofFootnotes
The authors declare no conflicts of interest.
This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
Identification
Copyright
© 2021 by the Editorial Council for the Journal of Prosthetic Dentistry.
