Abstract
Statement of problem
Temporomandibular disorders (TMDs) affect the muscles of mastication, the temporomandibular
joint, and associated structures. They are generally classified as muscular or articular and
are the main cause of pain in the orofacial region, eventually causing psychological
problems. However, the real burden of psychological disorders is unknown.
Purpose
The purpose of this systematic review and meta-analysis was to assess the prevalence
of psychological disorders in patients with TMDs.
Material and methods
The study was conducted through a bibliographic search carried out without initial
limit until July 2021 in the following electronic databases: MEDLINE/PubMed, Scopus,
and PsycINFO. Clinical observational studies investigating depression and somatization
in patients with TMD diagnosed by the Diagnostic Research for Temporomandibular Disorders
(RDC/TMD) criteria in muscular, articular, and disc disorders were included. A descriptive
analysis of the included studies and a meta-analysis for the prevalence data were
performed for the synthesis of evidence.
Results
A total of 2320 studies were found, of which 48 complete articles were assessed for
eligibility and 22 were included in the analysis. The general prevalence of depression
and moderate and severe somatization in patients diagnosed with TMD was estimated
at 43.0% (95% confidence interval (CI), 36.0% to 50.0%) and 60.0% (95% CI 52.0 - 67,
0%). The average overall score for depression was estimated at 0.92 (95% CI, 0.69-1.15),
being classified as moderate depression. The average overall score for somatization
was estimated at 1.09 (95% CI, 0.81-1.36), being classified as severe somatization.
All analyses showed high heterogeneity (I2>90%). Based on the quality assessment, 80.9% of studies included in the review had
low to moderate risk of bias.
Conclusions
Patients with TMDs who seek clinical care show a high prevalence of depression and
somatization.
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Article info
Publication history
Published online: September 13, 2022
Publication stage
In Press Corrected ProofFootnotes
Funding: Supported by CNPq and CAPES (Finance Code 001) for the master’s and PhD students’ scholarships.
Identification
Copyright
© 2022 by the Editorial Council for The Journal of Prosthetic Dentistry.
