Journal of Prosthetic Dentistry

Fixed prosthodontic rehabilitation for an adolescent patient with ectodermal dysplasia using a fully digital workflow: Two-year follow-up

Published:December 26, 2022DOI:


      Ectodermal dysplasia is a rare genetic disorder characterized by congenital abnormalities of tissues and structures of ectodermal origin, such as the hair, nails, skin, sweat glands, and teeth. Common dental characteristics include retained primary teeth, conical shaped incisors and canines, and hypodontia or oligodontia. Early prosthodontic intervention of young patients diagnosed with ectodermal dysplasia is essential as symptoms can have substantial esthetic, functional, and psychosocial impacts. This clinical report describes the fixed prosthodontic treatment of an adolescent patient with ectodermal dysplasia by using a fully digital workflow. Digital workflows streamlined the treatment process and allowed for esthetic, functional, and psychological improvements in an efficient manner.
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        • Itin P.
        • Fistarol S.K.
        Ectodermal dysplasias.
        Am J Med Genet. 2004; 131C: 45-51
        • Deshmukh S.
        • Prashanth S.
        Ectodermal dysplasia: a genetic review.
        Int J Clin Pediatr Dent. 2012; 5: 197-202
        • Clarke A.
        Hypohidrotic ectodermal dysplasia.
        J Med Genet. 1987; 24: 659-663
        • Hickey A.
        • Vergo Jr., T.J.
        Prosthetic treatments for patients with ectodermal dysplasia.
        J Prosthet Dent. 2001; 86: 364-368
        • Crawford P.J.
        • Aldred M.J.
        • Clarke A.
        Clinical and radiographic dental findings in X linked hypohidrotic ectodermal dysplasia.
        J Med Genet. 1991; 28: 181-185
        • Ruhin B.
        • Martinot V.
        • Lafforgue P.
        • Catteau B.
        • Manouvrier-Hanu S.
        • Feri J.
        Pure ectodermal dysplasia: retrospective study of 16 cases and literature review.
        Cleft Palate Craniofac J. 2001; 38: 504-518
        • Schnabl D.
        • Grunert I.
        • Schmuth M.
        • Kapferer-Seebacher I.
        Prosthetic rehabilitation of patients with hypohidrotic ectodermal dysplasia: a systematic review.
        J Oral Rehabil. 2018; 45: 555-570
        • Montanari M.
        • Callea M.
        • Battelli F.
        • Piana G.
        Oral rehabilitation of children with ectodermal dysplasia.
        BMJ Case Rep. 2012; 21: 29-52
        • Shigli A.
        • Reddy R.P.
        • Hugar S.M.
        • Deshpande D.
        Hypohidrotic ectodermal dysplasia: a unique approach to esthetic and prosthetic management: a case report.
        J Indian Soc Pedod Prev Dent. 2005; 23: 31-34
        • Kearns G.
        • Sharma A.
        • Perrott D.
        • Schmidt B.
        • Kaban L.
        • Vargervik K.
        Placement of endosseous implants in children and adolescents with hereditary ectodermal dysplasia.
        Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999; 88: 5-10
        • Locker D.
        • Jokovic A.
        • Prakash P.
        • Tompson B.
        Oral health-related quality of life of children with oligodontia.
        Int J Paediatr Dent. 2010; 20: 8-14
        • Saltnes S.S.
        • Jensen J.L.
        • Sæves R.
        • Nordgarden H.
        • Geirdal A.Ø.
        Associations between ectodermal dysplasia, psychological distress and quality of life in a group of adults with oligodontia.
        Acta Odontol Scand. 2017; 75: 564-572
        • Cronin Jr., R.J.
        • Oesterle L.J.
        Implant use in growing patients. Treatment planning concerns.
        Dent Clin North Am. 1998; 42: 1-34
        • Bahrami M.
        • Alsharbaty M.H.
        Prosthodontic rehabilitation of hypohidrotic ectodermal dysplasia in two young sisters with fixed prostheses: clinical case report.
        Dent Hypotheses. 2019; 10: 76
        • Krishnamurthy D.M.
        • Singh R.
        • Mistry G.
        Interim three-dimensional printed overlay prothesis for an adolescent patient with oligodontia.
        J Indian Prosthodont Soc. 2021; 21: 304-307
        • Toomarian L.
        • Ardakani M.R.
        • Ramezani J.
        • Adli A.R.
        • Tabari Z.A.
        Using implants for prosthodontic rehabilitation of a 4-year-old with ectodermal dysplasia.
        Gen Dent. 2014; 62: e1-e5
        • Thilander B.
        • Odman J.
        • Grondahl K.
        • Lekholm U.
        Aspects on osseointegrated implants inserted in growing jaws. A biometric and radiographic study in the young pig.
        Eur J Orthod. 1992; 14: 99-109
        • Chrcanovic B.R.
        Dental implants in patients with ectodermal dysplasia: a systematic review.
        J Craniomaxillofac Surg. 2018; 46: 1211-1217
        • McGarry T.J.
        • Nimmo A.
        • Skiba J.F.
        • et al.
        Classification system for partial edentulism.
        J Prosthodont. 2002; 11: 181-193
        • Pietrokovski J.
        • Massler M.
        Alveolar ridge resorption following tooth extraction.
        J Prosthet Dent. 1967; 17: 21-27
        • Goodacre B.J.
        • Swamidass R.S.
        • Lozada J.
        • et al.
        A 3D-printed guide for lateral approach sinus grafting: a dental technique.
        J Prosthet Dent. 2018; 119: 897-901
        • Chochlidakis K.M.
        • Papaspyridakos P.
        • Geminiani A.
        • Chen C.J.
        • Feng I.J.
        • Ercoli C.
        Digital versus conventional impressions for fixed prosthodontics: a systematic review and meta-analysis.
        J Prosthet Dent. 2016; 116: 184-190