Journal of Prosthetic Dentistry
Systematic Review|Articles in Press

Evaluation of bond strength of glass and resin-ceramics with laser phototherapy: A systematic review and meta-analysis of in vitro studies


      Statement of problem

      Laser phototherapy has been studied as a surface treatment capable of increasing the adhesion of cement to the ceramic surface. However, the bond strength of glass and resin-ceramics after laser phototherapy is unclear.


      The objective of this systematic review and meta-analysis was to compare the bond strength of glass and resin-ceramics using laser therapy and conventional hydrofluoric acid etching.

      Material and methods

      This systematic review and meta-analysis followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and was registered in the Open Science Framework (OSF) for in vitro studies. A population, intervention, control, and outcome (PICO) question was formulated: “Does phototherapy promote better bond strength in glass and resin-ceramics than conventional hydrofluoric acid etching?” A literature search was performed in PubMed/MEDLINE, Embase, Web of Science, Scopus, Cochrane Library, and ProQuest databases up to January 2023. The Joanna Briggs Institute critical assessment guidelines for quasi-experimental studies were used for quality assessment. The meta-analysis was based on the inverse variance (IV) method (α=.05).


      A total of 6 in vitro studies published between 2007 and 2019 with a total number of 348 specimens were included for qualitative analysis; 1 study had a positive effect. Five of the studies were included in the meta-analysis, which indicated a significant decrease for feldspathic ceramics that received laser phototherapy and lithium disilicate (P=.002; MD: −2.15; 95% CI: −3.53 to −0.77; I2=89%, P<.01) and (P<.01; MD: −2.13; 95% CI: −2.99 to −1.27; I2=82%, P<.01), respectively.


      Laser irradiation as surface etching of glass ceramics does not produce a bond strength equal to that of conventional hydrofluoric acid etching.
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        • Cruz M.E.M.
        • Simões R.
        • Martins S.B.
        • Trindade F.Z.
        • Dovigo L.N.
        • Fonseca R.G.
        Influence of simulated gastric juice on surface characteristics of CAD-CAM monolithic materials.
        J Prosthet Dent. 2020; 123: 483-490
        • Denry I.
        • Holloway J.A.
        Ceramics for dental applications: a review.
        Materials (Basel). 2010; 3: 351-368
        • Spitznagel F.A.
        • Horvath S.D.
        • Guess P.C.
        • Blatz M.B.
        Resin bond to indirect composite and new ceramic/polymer materials: a review of the literature.
        J Esthet Restor Dent. 2014; 26: 382-393
        • Cotes C.
        • de Carvalho R.F.
        • Kimpara E.T.
        • Leite F.P.
        • Ozcan M.
        Can heat treatment procedures of pre-hydrolyzed silane replace hydrofluoric acid in the adhesion of resin cement to feldspathic ceramic?.
        J Adhes Dent. 2013; 15: 569-574
        • Venturini A.B.
        • Prochnow C.
        • Rambo D.
        • Gundel A.
        • Valandro L.F.
        Effect of hydrofluoric acid concentration on resin adhesion to a feldspathic ceramic.
        J Adhes Dent. 2015; 17: 313-320
        • Blatz M.B.
        • Sadan A.
        • Kern M.
        Resin-ceramic bonding: a review of the literature.
        J Prosthet Dent. 2003; 89: 268-274
        • El Zhawi H.
        • Kaizer M.R.
        • Chughtai A.
        • Moraes R.R.
        • Zhang Y.
        Polymer infiltrated ceramic network structures for resistance to fatigue fracture and wear.
        Dent Mater. 2016; 32: 1352-1361
        • Vargas M.A.
        • Bergeron C.
        • Diaz-Arnold A.
        Cementing all-ceramic restorations.
        J Am Dent Assoc. 2011; 142: 20S-24S
        • Azevedo V.L.B.
        • Castro E.F.
        • Bonvent J.
        • et al.
        Surface treatments on CAD/CAM glass–ceramics: Influence on roughness, topography, and bond strength.
        J Esthet Restor Dent. 2021; 33: 739-749
        • Kirmali O.
        • Kapdan A.
        • Kustarci A.
        • Er K.
        Veneer ceramic to Y-TZP bonding: comparison of different surface treatments.
        J Prosthodont. 2015; 25: 324-329
        • Liu L.
        • Liu S.
        • Song X.
        • et al.
        Effect of Nd: YAG laser irradiation on surface properties and bond strength of zirconia ceramics.
        Lasers Med Sci. 2015; 30: 627-634
        • Alavi S.
        • Birang R.
        • Hajizadeh F.
        • Banimostafaee H.
        Effect of bracket bonding with Er: YAG laser on nanomechanical properties of enamel.
        Dent Res J (Isfahan). 2014; 11: 49-55
        • Ahrari F.
        • Boruziniat A.
        • Alirezaei M.
        Surface treatment with a fractional CO2 laser enhances shear bond strength of resin cement to zirconia.
        Laser Ther. 2016; 25: 19-26
        • Vohra F.
        • Labban N.
        • Al-Hussaini A.
        • et al.
        Influence of Er;Cr: YSGG laser on shear bond strength and color stability of lithium disilicate ceramics: an in vitro study.
        Photobiomodul Photomed Laser Surg. 2019; 37: 483-488
        • Paula Eduardo C.
        • Bello-Silva M.S.
        • Moretto S.G.
        • et al.
        Microtensile bond strength of composite resin to glass-infiltrated alumina composite conditioned with Er,Cr:YSGG laser.
        Lasers Med Sci. 2012; 27: 7-14
        • Gökçe B.
        • Ozpinar B.
        • Dündar M.
        • Cömlekoglu E.
        • Sen B.H.
        • Güngör M.A.
        Bond strengths of all-ceramics: acid vs laser etching.
        Oper Dent. 2007; 32: 173-178
        • Bitencourt S.B.
        • Ferreira L.C.
        • Mazza L.C.
        • Dos Santos D.M.
        • Pesqueira A.A.
        • Theodoro L.H.
        Effect of laser irradiation on bond strength between zirconia and resin cement or veneer ceramic: a systematic review and meta-analysis.
        J Indian Prosthodont Soc. 2021; 21: 125-137
        • Page M.J.
        • McKenzie J.E.
        • Bossuyt P.M.
        • et al.
        The PRISMA 2020 statement: an updated guideline for reporting systematic reviews.
        Syst Rev. 2021; 10: 89
        • Bento V.A.A.
        • Gomes J.M.L.
        • Lemos C.A.A.
        • Limirio J.P.J.O.
        • Rosa C.D.D.R.D.
        • Pellizzer E.P.
        Prevalence of proximal contact loss between implant-supported prostheses and adjacent natural teeth: a systematic review and meta-analysis.
        J Prosthet Dent. 19 July 2021; ([Epub ahead of print.])
        • de Oliveira Limírio J.P.J.
        • Lemos C.A.A.
        • de Luna Gomes J.M.
        • Minatel L.
        • Alves Rezende M.C.R.
        • Pellizzer E.P.
        A clinical comparison of 1-piece versus 2-piece implants: a systematic review and meta-analysis.
        J Prosthet Dent. 2020; 124: 439-445
        • Godfrey C.
        • Harrison M.
        Systematic review resource package.
        in: The Joanna Briggs institute method for systematic review research quick reference GuideQueen’s Joanna Briggs collaboration. 2010 (Kingston, ON.) ([Visited March 03, 2023])
        • Gorler O.
        • Saygin A.G.
        Comparative evaluation of effects of laser modalities on shear bond strengths of veneering porcelains to laser sintered substructures: an in vitro study.
        Photomed Laser Surg. 2017; 35: 338-344
        • Gorler O.
        • Hubbezoglu I.
        • Ulgey M.
        • Zan R.
        • Guner K.
        Shear bond strength of composite and ceromer superstructures to direct laser sintered and Ni-Cr-Based infrastructures treated with KTP, Nd:YAG, and Er:YAG lasers: an experimental study.
        Photomed Laser Surg. 2018; 36: 203-208
        • Alp G.
        • Subaşı M.G.
        • Johnston W.M.
        • Yilmaz B.
        Effect of different resin cements and surface treatments on the shear bond strength of ceramic-glass polymer materials.
        J Prosthet Dent. 2018; 120: 454-461
        • Małysa A.
        • Weżgowiec J.
        • Danel D.
        • Boening K.
        • Walczak K.
        • Więckiewicz M.
        Bond strength of modern self-adhesive resin cements to human dentin and different CAD/CAM ceramics.
        Acta Bioeng Biomech. 2020; 22: 25-34
        • Cvikl B.
        • Moser G.
        • Wernisch J.
        • Raabe M.
        • Gruber R.
        • Moritz A.
        The impact of Er,Cr:YSGG laser on the shear strength of the bond between dentin and ceramic is dependent on the adhesive material.
        Lasers Med Sci. 2012; 27: 717-722
        • Akyıl M.Ş.
        • Yılmaz A.
        • Bayındır F.
        • Duymuş Z.Y.
        Microtensile bond strength of resin cement to a feldspathic ceramic.
        Photomed Laser Surg. 2011; 29: 197-203
        • Shiu P.
        • De Souza-Zaroni W.C.
        • Eduardo Cde P.
        • Youssef M.N.
        Effect of feldspathic ceramic surface treatments on bond strength to resin cement.
        Photomed Laser Surg. 2007; 25: 291-296
        • Yavuz T.
        • Özyılmaz Ö.Y.
        • Dilber E.
        • Tobi E.S.
        • Kiliç H.Ş.
        Effect of different surface treatments on porcelain-resin bond strength.
        J Prosthodont. 2015; 26: 446-454
        • Dönmez M.B.
        • Yucel M.T.
        • Kilic I.
        • Okutan Y.
        Novel ceramic primer vs. conventional treatment methods: effects on roughness and bond strength of all-ceramic restorations.
        Am J Dent. 2018; 31: 249-252
        • Gamal A.E.
        • Medioni E.
        • Rocca J.P.
        • Fornaini C.
        • Brulat-Bouchard N.
        CO2 laser dentin surface treatment most effectively increased ceramic shear bond strength.
        Laser Ther. 2018; 27: 48-54
        • Barutcigil K.
        • Barutcigil Ç.
        • Kul E.
        • Özarslan M.M.
        • Buyukkaplan U.S.
        Effect of different surface treatments on bond strength of resin cement to a CAD/CAM restorative material.
        J Prosthodont. 2019; 28: 71-78
        • Al-Aali K.A.
        Effect of phototherapy on shear bond strength of resin cements to zirconia ceramics: a systematic review and meta-analysis of in-vitro studies.
        Photodyn Ther. 2018; 23: 58-62